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It can mean taking too many prescription pills. Drug abuse is when you turn to substances to get a certain feeling: pleasure, escape, relaxation and so on. Drug abuse can be damaging to relationships and the body—but usually, a person can stop if he or she wants to. That is not the case with addiction. Addiction is when you can’t stop using drugs or alcohol, even if you want to stop. Addiction drives you to keep using even if a substance is ruining your health,